Exploring the Impact of Chitosan Composites as Artificial Organs

Polymers

Sechul Chun¹  Iyyakkannu Sivanesan¹  Nazim Hasan²  Juhyun Shin³  Jae-Wook Oh³  Manikandan Muthu⁴  Gowsalya Blessing⁵  Judy Gopal⁵ 

[1] Department of Bioresources and Food Science, Institute of Natural Science and Agriculture, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 05029, Korea;Department of Chemistry, Faculty of Science, Jazan University, Jazan P. O. Box 114, Saudi Arabia;Department of Stem Cell and Regenerative Biotechnology, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 05029, Korea;Division of Research and Innovation, Department of Biotechnology, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences (SIMATS), Thandalam, Chennai 602105, Tamil Nadu, India;Laboratory of Neo Natural Farming, Chunnampet 603401, Tamil Nadu, India;

关键词: chitosan;    biomedical applications;    artificial organs;    composites;    tissue regeneration;   

DOI  :  10.3390/polym14081587

来源: DOAJ

【 摘 要 】

Chitosan and its allies have in multiple ways expanded into the medical, food, chemical, and biological industries and is still expanding. With its humble beginnings from marine shell wastes, the deacetylated form of chitin has come a long way in clinical practices. The biomedical applications of chitosan are truly a feather on its cap, with rarer aspects being chitosan’s role in tissue regeneration and artificial organs. Tissue regeneration is a highly advanced and sensitive biomedical application, and the very fact that chitosan is premiering here is an authentication of its ability to deliver. In this review, the various biomedical applications of chitosan are touched on briefly. The synthesis methodologies that are specific for tissue engineering and biomedical applications have been listed. What has been achieved using chitosan and chitosan composites in artificial organ research as well as tissue regeneration has been surveyed and presented. The lack of enthusiasm, as demonstrated by the very few reports online with respect to chitosan composites and artificial organs, is highlighted, and the reasons for this lapse speculated. What more needs be done to expand chitosan and its allies for a better utilization and exploitation to best benefit the construction of artificial organs and building of tissue analogs has been discussed.

【 授权许可】

Unknown