期刊论文详细信息
Beilstein Journal of Organic Chemistry | |
Coupling of α,α-difluoro-substituted organozinc reagents with 1-bromoalkynes | |
Alexander D. Dilman1  Marina I. Struchkova1  Alexander D. Volodin1  Artem A. Zemtsov1  Vitalij V. Levin1  | |
[1] N. D. Zelinsky Institute of Organic Chemistry, 119991 Moscow, Leninsky prosp. 47, Russian Federation; | |
关键词: 1-bromoalkynes; cross-coupling; organofluorine compounds; organozinc reagents; | |
DOI : 10.3762/bjoc.11.231 | |
来源: DOAJ |
【 摘 要 】
α,α-Difluoro-substituted organozinc reagents generated from conventional organozinc compounds and difluorocarbene couple with 1-bromoalkynes affording gem-difluorinated alkynes. The cross-coupling proceeds in the presence of catalytic amounts of copper iodide in dimethylformamide under ligand-free conditions.
【 授权许可】
Unknown