Longitudinal Changes of Mineral Concentrations in Preterm and Term Human Milk from Lactating Swiss Women

Nutrients

Lydie Beauport¹  Jean-François Tolsa¹  CélineJ. Fischer Fumeaux¹  CarlosA. De Castro²  SagarK. Thakkar²  Valentine Bordier³  Magalie Sabatier³  Marine Nicolas³  Michael Affolter³  Stéphane Dubascoux³  Peter Kastenmayer³  ClaraL. Garcia-Rodenas³  Janique Richoz Payot³  Mario Vigo³  Daniel Andrey³ 

[1] Clinic of Neonatology, Department Woman Mother Child, University Hospital of Lausanne, 1011 Lausanne, Switzerland;Nestle Research Singapore Hub, Société des Produits Nestlé SA, 29 Quality Road, Singapore 618802, Singapore;Nestlé Research, Société des Produits Nestlé SA, 1000 Lausanne, Switzerland;

关键词: human milk;    term;    preterm;    calcium;    phosphorus;    magnesium;    zinc;    iron;    copper;    iodine;    selenium;    potassium;    sodium;   

DOI  :  10.3390/nu11081855

来源: DOAJ

【 摘 要 】

An adequate mineral supply to preterm infants is essential for normal growth and development. This study aimed to compare the mineral contents of human milk (HM) from healthy mothers of preterm (28−32 weeks) and full term (>37 weeks) infants. Samples were collected weekly for eight weeks for the term group (n = 34) and, biweekly up to 16 weeks for the preterm group (n = 27). Iron, zinc, selenium, copper, iodine, calcium, magnesium, phosphorus, potassium, and sodium were quantitatively analyzed by Inductively Coupled Plasma-Mass Spectrometry. The mineral contents of both HM showed parallel compositional changes over the period of lactation, with occasional significant differences when compared at the same postpartum age. However, when the comparisons were performed at an equivalent postmenstrual age, preterm HM contained less zinc and copper from week 39 to 48 (p < 0.002) and less selenium from week 39 to 44 (p < 0.002) than term HM. This translates into ranges of differences (min−max) of 53% to 78%, 30% to 72%, and 11% to 33% lower for zinc, copper, and selenium, respectively. These data provide comprehensive information on the temporal changes of ten minerals in preterm HM and may help to increase the accuracy of the mineral fortification of milk for preterm consumption.

【 授权许可】

Unknown