Progress in Gelatin as Biomaterial for Tissue Engineering

Pharmaceutics

Martin Federico Desimone¹  Alireza Dolatshahi-Pirouz²  Jon Zarate³  Lidia Maeso³  Gorka Orive³  Itsasne Erezuma³  Izeia Lukin³  Taleb H. Al-Tel⁴ 

[1] Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto de Química y Metabolismo del Fármaco (IQUIMEFA), Facultad de Farmacia y Bioquímica Junín 956, Universidad de Buenos Aires, Buenos Aires 1113, Argentina;Department of Health Technology, Center for Intestinal Absorption and Transport of Biopharmaceuticals, Technical University of Denmark, 2800 Kgs Lyngby, Denmark;NanoBioCel Research Group, School of Pharmacy, University of the Basque Country (UPV/EHU), 01006 Vitoria-Gasteiz, Spain;Sharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates;

关键词: gelatin;    biomaterials;    regenerative medicine;    tissue engineering;   

DOI  :  10.3390/pharmaceutics14061177

来源: DOAJ

【 摘 要 】

Tissue engineering has become a medical alternative in this society with an ever-increasing lifespan. Advances in the areas of technology and biomaterials have facilitated the use of engineered constructs for medical issues. This review discusses on-going concerns and the latest developments in a widely employed biomaterial in the field of tissue engineering: gelatin. Emerging techniques including 3D bioprinting and gelatin functionalization have demonstrated better mimicking of native tissue by reinforcing gelatin-based systems, among others. This breakthrough facilitates, on the one hand, the manufacturing process when it comes to practicality and cost-effectiveness, which plays a key role in the transition towards clinical application. On the other hand, it can be concluded that gelatin could be considered as one of the promising biomaterials in future trends, in which the focus might be on the detection and diagnosis of diseases rather than treatment.

【 授权许可】

Unknown