Crystal structure of (+)-N-[(1R,5S,6S,9S)-5-hydroxymethyl-3,3,9-trimethyl-8-oxo-2,4,7-trioxabicyclo[4.3.0]nonan-9-yl]acetamide

Acta Crystallographica Section E: Crystallographic Communications

Tomoya Sugai¹  Shun Tsuzaki¹  Takaaki Sato¹  Noritaka Chida¹  Takeshi Oishi² 

[1] Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi 3-14-1, Kohoku-ku, Yokohama 223-8522, Japan;School of Medicine, Keio University, Hiyoshi 4-1-1, Kohoku-ku, Yokohama 223-8521, Japan;

关键词: crystal structure;    bicyclic compound;    1,3-dioxane;    oxolane;    hydrogen bond;    hydroxy group;   

DOI  :  10.1107/S2056989016006800

来源: DOAJ

【 摘 要 】

In the title compound, C12H19NO6, the six-membered 1,3-dioxane ring adopts a chair-like conformation. The seat of this chair, containing two O atoms, is essentially planar, with a maximum deviation of 0.0021 (12) Å. The five-membered oxolane ring cis-fused to the 1,3-dioxane ring adopts an envelope form. The bridgehead C atom at the flap, which is bonded to the tetrasubstituted C atom of the oxolane ring, deviates from the mean plane of other ring atoms by 0.539 (4) Å. In the crystal, classical O—H...O and N—H...O hydrogen bonds link the molecules into a sheet structure enclosing an R44(24) graph-set motif. Weak intermolecular C—H...O interactions support the sheet formation.

【 授权许可】

Unknown