Microalgae Biomolecules: Extraction, Separation and Purification Methods

Processes

Wilson G. Morais Júnior¹  Priscila S. Corrêa²  Teresa M. Mata²  Nídia S. Caetano²  António A. Martins² 

[1] CIETI, School of Engineering (ISEP), Polytechnic Institute of Porto (P.Porto), R. Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal;LEPABE—Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto (FEUP), R. Dr. Roberto Frias s/n, 4200-465 Porto, Portugal;

关键词: biomolecules;    chromatography;    cell disruption;    microalgae;    purification;    supercritical fluids;   

DOI  :  10.3390/pr9010010

来源: DOAJ

【 摘 要 】

Several microalgae species have been exploited due to their great biotechnological potential for the production of a range of biomolecules that can be applied in a large variety of industrial sectors. However, the major challenge of biotechnological processes is to make them economically viable, through the production of commercially valuable compounds. Most of these compounds are accumulated inside the cells, requiring efficient technologies for their extraction, recovery and purification. Recent improvements approaching physicochemical treatments (e.g., supercritical fluid extraction, ultrasound-assisted extraction, pulsed electric fields, among others) and processes without solvents are seeking to establish sustainable and scalable technologies to obtain target products from microalgae with high efficiency and purity. This article reviews the currently available approaches reported in literature, highlighting some examples covering recent granted patents for the microalgae’s components extraction, recovery and purification, at small and large scales, in accordance with the worldwide trend of transition to bio-based products.

【 授权许可】

Unknown