Genotoxicity of indium tin oxide by comet test

Frontiers in Genetics

İbrahim Hakkı Ciğerci¹  Recep Liman²  Muhsin Konuk³ 

[1] Afyon Kocatepe University;Usak University;Üsküdar University;

关键词: Allium;    Comet Assay;    DNA Damage;    Genotoxicity;    Indium Tin Oxide;   

DOI  :  10.3389/conf.fgene.2015.01.00040

来源: DOAJ

【 摘 要 】

Indium tin oxide (ITO) is used for liquid crystal display (LCDs), electrochromic displays, flat panel displays, field emission displays, touch or laptop computer screens, cell phones, energy conserving architectural windows, defogging aircraft and automobile windows, heat-reflecting coatings to increase light bulb efficiency, gas sensors, antistatic window coatings, wear resistant layers on glass, nanowires and nanorods because of its unique properties of high electrical conductivity, transparency and mechanical resistance.Genotoxic effects of ITO were investigated on the root cells of Allium cepa by Comet assay.A. cepa roots were treated with the aqueous dispersions of ITO at 5 different concentrations (12.5, 25, 50, 75, and 100 ppm) for 4 h. A significant increase in DNA damage was a observed at all concentrations of ITO by Comet assay. These result indicate that ITO exhibit genotoxic activity in A. cepa root meristematic cells.

【 授权许可】

Unknown