Microbial production of rhamnolipids using sugars as carbon sources

Microbial Cell Factories

Qingxin Li¹  Yun Nian Tan² 

[1] Institute of Chemical and Engineering Sciences, Agency for Science, Technology and Research;School of Chemical and Biomedical Engineering, Nanyang Technological University;

关键词: Rhamnolipids;    Cellulose;    Waste;    Biotransformation;    Fermentation;   

DOI  :  10.1186/s12934-018-0938-3

来源: DOAJ

【 摘 要 】

Abstract Rhamnolipids are a class of biosurfactants with effective surface-active properties. The high cost of microbial production of rhamnolipids largely affects their commercial applications. To reduce the production post, research has been carried out in screening more powerful strains, engineering microbes with higher biosurfactant yields and exploring cheaper substrates to reduce the production cost. Extensive refining is required for biosurfactant production using oils and oil-containing wastes, necessitating the use of complex and expensive biosurfactant recovery methods such as extraction with solvents or acid precipitation. As raw materials normally can account for 10–30% of the overall production cost, sugars have been proven to be an alternative carbon source for microbial production of rhamnolipids due to its lower costs and straightforward processing techniques. Studies have thus been focused on using tropical agroindustrial crop residues as renewable substrates. Herein, we reviewed studies that are using sugar-containing substrates as carbon sources for producing rhamnolipids. We speculate that sugars derived from agricultural wastes rich in cellulose and sugar-containing wastes are potential carbon sources in fermentation while challenges still remain in large scales.

【 授权许可】

Unknown