Separate and combined effects of cold dialysis and intradialytic exercise on the thermoregulatory responses of hemodialysis patients: a randomized-cross-over study

BMC Nephrology

Christoforos D. Giannaki¹  Argyro A. Krase²  Andreas D. Flouris²  Ioannis Stefanidis³  Giorgos K. Sakkas⁴  Christina Karatzaferi⁴ 

[1] Department of Life and Health Sciences, University of Nicosia;FAME Lab, School of Physical Education, Sport Science and Dietetics, University of Thessaly;School of Health Sciences, Department of Medicine, Division of Nephrology, University of Thessaly;School of Physical Education, Sport Science and Dietetics, University of Thessaly;

关键词: Cold dialysis;    Body temperature during dialysis;    Dialysis temperature;    Thermal balance;   

DOI  :  10.1186/s12882-020-02167-z

来源: DOAJ

【 摘 要 】

Abstract Background The separate and combined effects of intradialytic exercise training (IET) and cold dialysis (CD) on patient thermoregulation remain unknown. This study assessed the thermoregulatory responses of hemodialysis patients under four different hemodialysis protocols: a) one typical dialysis (TD) protocol (dialysate temperature at 37 °C), b) one cold dialysis (CD) protocol (dialysate temperature at 35 °C), c) one typical dialysis protocol which included a single exercise bout (TD + E), d) one cold dialysis protocol which included a single exercise bout (CD + E). Methods Ten hemodialysis patients (57.2 ± 14.9 years) participated in this randomized, cross-over study. Core and skin temperatures were measured using an ingestible telemetric pill and by four wireless iButtons attached on the skin, respectively. Body heat storage (S) calculated using the thermometric method proposed by Burton. Results The TD and TD + E protocols were associated with increased S leading to moderate effect size increases in core body temperature (as high as 0.4 °C). The low temperature of the dialysate during the CD and the CD + E protocols prevented the rise in S and core temperature (p > 0.05), even during the period that IET took place. Conclusions TD and IET are accompanied by a moderate level of hyperthermia, which can be offset by CD. We recommended that CD or with IET can prevent the excessive rise of S. Trial registration Clinical Trial Registry number: NCT03905551 ( clinicaltrials.gov ), DOR: 05/04/2019,

【 授权许可】

Unknown