Solitary castrate-resistant prostate cancer metastasis to adrenal gland with concordant intense avidity on PSMA and FDG PET

Urology Case Reports

Matthew J. Roberts¹  Reece Phillips²  Nicholas J. Rukin³  Stephen McGeorge⁴  Jamie Reynolds⁵ 

[1] Department of Urology, Redcliffe Hospital, Anzac Avenue, Redcliffe, Queensland, 4020, Australia;Faculty of Medicine, The University of Queensland, Herston, Queensland, 4006, Australia;Department of Urology, Redcliffe Hospital, Anzac Avenue, Redcliffe, Queensland, 4020, Australia;Department of Urology, Royal Brisbane and Women's Hospital, Butterfield St, Herston, Queensland, 4029, Australia;Faculty of Medicine, The University of Queensland, Herston, Queensland, 4006, Australia;

关键词: Prostate cancer;    Prostate specific membrane antigen;    PSMA;    Fluorodeoxyglucose;    FDG;    Adrenalectomy;   

DOI  :  

来源: DOAJ

【 摘 要 】

Isolated prostate cancer metastasis to the adrenal gland is rare. We report a case of concordant high uptake in a solitary adrenal metastasis on both prostate-specific membrane antigen and fluorodeoxyglucose positron-emission tomography in a patient with castrate-resistant prostate cancer. Good initial biochemical response was achieved with laparoscopic adrenalectomy. The patient developed lymph node recurrence 12 months later, although remains asymptomatic on hormonal treatment 22 months post-operatively, in keeping with prior results for metastasis-directed therapy which can delay time to additional treatment. Application of dual tracer PET can be valuable for prostate cancer staging and guidance of metastasis-directed treatment.

【 授权许可】

Unknown