期刊论文详细信息
Molecules | |
Michael Addition Reaction Catalyzed by Imidazolium Chloride to Protect Amino Groups and Construct Medium Ring Heterocycles | |
Wen Luo1  Yanwu Li1  Jianyong Yuan1  Xuetong Wang1  Suqin Shang1  Dan Li1  Ying Zhang1  Zeshu Dai1  Zhiyao Li1  Qingqiang Tian1  | |
[1] Department of Medicinal Chemistry, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China; | |
关键词: imidazolium chloride; amino protection; michael addition reaction; amino deprotection; solvent-free; seven-membered ring; | |
DOI : 10.3390/molecules24234224 | |
来源: DOAJ |
【 摘 要 】
An effective approach for amino protection and construction of a seven-membered ring has been developed. The method uses imidazolium chloride to carry out the Michael addition reaction at low temperatures and perform amino deprotection or construction of a seven-membered ring at high temperatures.
【 授权许可】
Unknown