期刊论文详细信息
Sensors
Advances in Electrochemical Impedance Spectroscopy Detection of Endocrine Disruptors
Camelia Bala1  Lucian-Gabriel Zamfir1  Mihaela Puiu1 
[1] R&D Center LaborQ, University of Bucharest, 4-12 Regina Elisabeta Blvd., 030018 Bucharest, Romania;
关键词: endocrine;    biosensor;    impedance;    MIP;    immunosensor;    aptasensor;   
DOI  :  10.3390/s20226443
来源: DOAJ
【 摘 要 】

Endocrine disruptors (EDs) are contaminants that may mimic or interfere with the body’s hormones, hampering the normal functions of the endocrine system in humans and animals. These substances, either natural or man-made, are involved in development, breeding, and immunity, causing a wide range of diseases and disorders. The traditional detection methods such as enzyme linked immunosorbent assay (ELISA) and chromatography are still the golden techniques for EDs detection due to their high sensitivity, robustness, and accuracy. Nevertheless, they have the disadvantage of being expensive and time-consuming, requiring bulky equipment or skilled personnel. On the other hand, early stage detection of EDs on-the-field requires portable devices fulfilling the Affordable, Sensitive, Specific, User-friendly, Rapid and Robust, Equipment free, Deliverable to end users (ASSURED) norms. Electrochemical impedance spectroscopy (EIS)-based sensors can be easily implemented in fully automated, sample-to-answer devices by integrating electrodes in microfluidic chips. The latest achievements on EIS-based sensors are discussed and critically assessed.

【 授权许可】

Unknown   

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