Impact of Tobacco Smoking on Outcomes of Radiotherapy: A Narrative Review

Current Oncology

Jacek Jassem¹  Adrian Perdyan² 

[1] Department of Oncology and Radiotherapy, Medical University of Gdańsk, 80-214 Gdańsk, Poland;International Research Agenda 3P Medicine Laboratory, Medical University of Gdańsk, 80-211 Gdańsk, Poland;

关键词: tobacco smoking;    smoking cessation;    radiotherapy;    cancer;    treatment outcome;   

DOI  :  10.3390/curroncol29040186

来源: DOAJ

【 摘 要 】

The carcinogenic role of tobacco smoking is well recognized, but the detrimental effects of continued smoking after a cancer diagnosis have been underestimated. Radiotherapy is among the main treatment modalities for cancer. We reviewed the literature data concerning the impact of tobacco smoking on treatment outcomes in radiotherapy-managed patients with various malignancies. Most of the analyzed studies demonstrated the detrimental effect of smoking on overall survival, tumor control, quality of life, treatment toxicity, and the incidence of second primary malignancies. Healthcare professionals should use the cancer diagnosis and treatment as a teachable moment and recommend their patients to immediately cease smoking. Wherever possible, cancer patients should undergo an intensive smoking-cessation program, including behavioral and pharmacologic therapy.

【 授权许可】

Unknown