期刊论文详细信息
| Molecular Medicine | |
| IKK-mediated CYLD phosphorylation and cellular redox activity | |
| 关键词: CYLD; IKK; NRF2; NF-κB; RIPK1; | |
| DOI : 10.1186/s10020-022-00439-y | |
| 来源: DOAJ | |
【 摘 要 】
Abstract Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about the functioning of the mechanisms that will be effective in the pathogenesis require clarification.
【 授权许可】
Unknown
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