期刊论文详细信息
Biosensors
Laser-Induced Graphene-Based Wearable Epidermal Ion-Selective Sensors for Noninvasive Multiplexed Sweat Analysis
Jian Fu1  Hande Chen1  Jianjun Liao2  Zihan Sun2  Chengjun Ge2  Xiangya Zhang2  Shiwei Lin3  Hewei Si3 
[1] Hainan Unican Science and Technology Innovation Institute, Haikou 571152, China;Key Laboratory of Agro-Forestry Environmental Processes and Ecological Regulation of Hainan Province, School of Ecological and Environmental Sciences, Hainan University, Haikou 570228, China;School of Materials Science and Engineering, Hainan University, Haikou 570228, China;
关键词: laser-induced graphene;    electrochemical sensors;    sweat analysis;    wearable devices;   
DOI  :  10.3390/bios12060397
来源: DOAJ
【 摘 要 】

Wearable sweat sensors are a rapidly rising research area owing to their convenience for personal healthcare and disease diagnosis in a real-time and noninvasive manner. However, the fast and scalable fabrication of flexible electrodes remains a major challenge. Here, we develop a wearable epidermal sensor for multiplexed sweat analysis based on the laser-induced graphene (LIG) technique. This simple and mask-free technique allows the direct manufacturing of graphene electrode patterns on commercial polyimide foils. The resulting LIG devices can simultaneously monitor the pH, Na+, and K+ levels in sweat with the sensitivities of 51.5 mV/decade (pH), 45.4 mV/decade (Na+), and 43.3 mV/decade (K+), respectively. Good reproducibility, stability, and selectivity are also observed. On-body testing of the LIG-based sensor integrated with a flexible printed circuit board during stationary cycling demonstrates its capability for real-time sweat analysis. The concentrations of ions can be remotely and wirelessly transmitted to a custom-developed smartphone application during the period in which the sensor user performs physical activities. Owing to the unique advantages of LIG technique, including facile fabrication, mass production, and versatile, more physiological signals (glucose, uric acid, tyrosine, etc.) could be easily expanded into the LIG-based wearable sensors to reflect the health status or clinical needs of individuals.

【 授权许可】

Unknown   

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