Bringing Again Noble Metal Nanoparticles to the Forefront of Cancer Therapy

Frontiers in Bioengineering and Biotechnology

关键词: persistence;    oncology;    nanoparticles;    theranostic agent;    clinical translation;    nanomedicine;   

DOI  :  10.3389/fbioe.2018.00143

来源: DOAJ

【 摘 要 】

Nanomaterials have attracted increasing interest for their potentiality to revolutionize the diagnosis and treatment of many diseases, especially neoplasms. Interestingly, there is a huge imbalance between the number of proposed nanoplatforms and the few ones approved for clinical applications. This disequilibrium affects in particular noble metal nanoparticles (NPs), that present no-approved platform and very few candidates in clinical trials because of the issue of persistence. In this perspective, we discuss if nanomedicine is generally keeping its promises with a focus on the approach that could fill the gap between NPs and oncology in the next future: the ultrasmall-in-nano.

【 授权许可】

Unknown