Low-Intensity Resistance Training with Moderate Blood Flow Restriction Appears Safe and Increases Skeletal Muscle Strength and Size in Cardiovascular Surgery Patients: A Pilot Study

Journal of Clinical Medicine

Takahisa Nasuno¹  Hiroyuki Kaneda¹  Shigeru Toyoda¹  Toshiaki Nakajima¹  Teruo Inoue¹  Hiroshi Yagi¹  Hironaga Ogawa²  Ikuko Shibasaki²  Hirotsugu Fukuda²  Azusa Uematsu³  Satoshi Katayanagi⁴  Hayato Ishizaka⁴  Takashi Mizushima⁴  Yuta Mizushima⁴  Tomohiro Yasuda⁵  Tibor Hortobágyi⁶ 

[1] Department of Cardiovascular Medicine, School of Medicine, Dokkyo Medical University, Shimotsuga-gun, Tochigi 321-0293, Japan;Department of Cardiovascular Surgery, School of Medicine, Dokkyo Medical University, Shimotsuga-gun, Tochigi 321-0293, Japan;Department of Health and Sport Sciences, Premedical Sciences, Dokkyo Medical University, Shimotsuga-gun, Tochigi 321-0293, Japan;Department of Rehabilitation, Dokkyo Medical University Hospital, Shimotsuga-gun, Tochigi 321-0293, Japan;School of Nursing, Seirei Christopher University, Hamamatsu, Shizuoka 433-8558, Japan;University Medical Center Groningen, University of Groningen, Groningen, 9713 GZ Groningen, The Netherlands;

关键词: cardiac surgery;    resistance exercise;    muscle hypertrophy;    cardiac rehabilitation;    moderate blood flow restriction;    KAATSU training;   

DOI  :  10.3390/jcm10030547

来源: DOAJ

【 摘 要 】

We examined the safety and the effects of low-intensity resistance training (RT) with moderate blood flow restriction (KAATSU RT) on muscle strength and size in patients early after cardiac surgery. Cardiac patients (age 69.6 ± 12.6 years, n = 21, M = 18) were randomly assigned to the control (n = 10) and the KAATSU RT group (n = 11). All patients had received a standard aerobic cardiac rehabilitation program. The KAATSU RT group additionally executed low-intensity leg extension and leg press exercises with moderate blood flow restriction twice a week for 3 months. RT-intensity and volume were increased gradually. We evaluated the anterior mid-thigh thickness (MTH), skeletal muscle mass index (SMI), handgrip strength, knee extensor strength, and walking speed at baseline, 5–7 days after cardiac surgery, and after 3 months. A physician monitored the electrocardiogram, rate of perceived exertion, and the color of the lower limbs during KAATSU RT. Creatine phosphokinase (CPK) and D-dimer were measured at baseline and after 3 months. There were no side effects during KAATSU RT. CPK and D-dimer were normal after 3 months. MTH, SMI, walking speed, and knee extensor strength increased after 3 months with KAATSU RT compared with baseline. Relatively low vs. high physical functioning patients tended to increase physical function more after 3 months with KAATSU RT. Low-intensity KAATSU RT as an adjuvant to standard cardiac rehabilitation can safely increase skeletal muscle strength and size in cardiovascular surgery patients.

【 授权许可】

Unknown