Effects of L-lysine·H2SO4 product on the intestinal morphology and liver pathology using broiler model

Journal of Animal Science and Biotechnology

Wenfeng Ma¹  Shihai Zhang²  Haitao Yu³  Shiyan Qiao³  Xiangfang Zeng³  Jie Zhang³  Xi Ma³  Ting He³  Hongmin Jia³ 

[1] College of Animal Science and Technology, Henan University of Science and Technology;Guangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University;State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University;

关键词: Broilers;    Intestinal morphology;    Liver pathology;    L-lysine·H2SO4;   

DOI  :  10.1186/s40104-019-0318-9

来源: DOAJ

【 摘 要 】

Abstract Background Lysine is used widely in livestock production due to the shortage of feed protein resources. L-lysine·H2SO4 contains L-lysine sulphate as well as fermentation co-products which contain other amino acids and phosphorus. However, there are few articles about L-lysine·H2SO4 product regarding intestinal morphology and liver pathology of broiler chickens. In this article, we focus on the absorption and metabolism of L-lysine·H2SO4 revealed in the variation of intestinal morphology and liver pathology to determine the tolerance of chicks for L-lysine·H2SO4. Methods To evaluate the tolerance of broilers for L-lysine·H2SO4, 240 one day old broilers were allocated randomly to one of five dietary treatments which included corn-soybean diets containing 0, 1%, 4%, 7% or 10% L-lysine·H2SO4 (L-lysine content = 55%). Results Supplementation of 1% L-lysine·H2SO4 in the diet had no negative effects. However, 4%, 7% or 10% L-lysine·H2SO4 supplementation produced negative responses on broiler performance, carcass characteristics, blood biochemistry, and particularly on intestinal morphology and liver pathology compared with broilers fed the control diet. Conclusion Our results show that supplementation with 1% L-lysine·H2SO4 had no negative effects on performance, carcass characteristics, blood biochemistry, intestinal morphology and liver pathology in broilers, but supplementation with 4%, 7% or 10% L-lysine·H2SO4 produced a negative response, particularly with respect to intestinal morphology and liver pathology.

【 授权许可】

Unknown