Whole-Genome Sequencing of Drug-Resistant Mycobacterium tuberculosis Strains, Tunisia, 2012–2016

Emerging Infectious Diseases

关键词: WGS;    MDR-TB;    XDR-TB;    cgMLST;    drug resistance marker;    tuberculosis and other mycobacteria;   

DOI  :  10.3201/eid2503.181370

来源: DOAJ

【 摘 要 】

To investigate transmission of drug-resistant strains of Mycobacterium tuberculosis in Tunisia, we performed whole-genome sequencing on 46 multidrug-resistant strains isolated during 2012–2016. Core-genome multilocus sequence typing grouped 30 strains (65.2%) into 3 clusters, indicating extensive recent transmission and Haarlem clone predominance. Whole-genome sequencing might help public health services undertake appropriate control actions.

【 授权许可】

Unknown