A case series of children and young people admitted to a tertiary care hospital in Germany with COVID-19

BMC Infectious Diseases

Hanna Renk¹  Oliver Heinzel¹  Jonathan Remppis¹  Rupert Handgretinger¹  Malte Kohns Vasconcelos²  Tina Ganzenmueller³ 

[1] Department of Haematology and Oncology, University Children’s Hospital Tuebingen;Institute for Medical Microbiology and Hospital Hygiene, Heinrich Heine University Düsseldorf;Institute for Medical Virology, University Hospital Tuebingen;

关键词: COVID-19;    SARS CoV-2 infection;    Children;    Comorbidity;    Inpatients;   

DOI  :  10.1186/s12879-021-05791-8

来源: DOAJ

【 摘 要 】

Abstract Background While our knowledge about COVID-19 in adults has rapidly increased, data on the course of disease and outcome in children with different comorbidities is still limited. Methods Prospective, observational study at a tertiary care children’s hospital in southern Germany. Clinical and virology data from all paediatric patients admitted with SARS-CoV-2 infection at our hospital were prospectively assessed. Results Between March and November 2020, 14 patients were admitted with COVID-19. One patient was admitted a second time with COVID-19 6 months after initial disease. Among seven patients with severe underlying comorbidities, three developed multisystem inflammatory syndrome (MIS-C), two were admitted to the paediatric intensive care unit. One patient needed invasive ventilation. Another patient died shortly after discharge of COVID-19-related complications. Conclusions While COVID-19 generally causes mild disease in children, severe respiratory illness and MIS-C occur, in some cases with fatal outcome. Children with underlying diseases might be at special risk for severe disease.

【 授权许可】

Unknown