Anodized Biomedical Stainless-Steel Mini-Implant for Rapid Recovery in a Rabbit Model

Metals

Bai-Hung Huang¹  Keng-Liang Ou¹  Wen-Chien Lan²  Hsin-Yu Tsai³  Takashi Saito³  Chen-Han Lee⁴  Yung-Chieh Cho⁴  Wei-Chiang Hung⁵  Mao-Suan Huang⁵ 

[1] Biomedical Technology R & D Center, China Medical University, Taichung 404, Taiwan;Department of Oral Hygiene Care, Ching Kuo Institute of Management and Health, Keelung 203, Taiwan;Division of Clinical Cariology and Endodontology, Department of Oral Rehabilitation, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido 061-0293, Japan;School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan;School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan;

关键词: anodization;    stability;    mini-implant;    biomedical stainless-steel;    biocompatibility;   

DOI  :  10.3390/met11101575

来源: DOAJ

【 摘 要 】

The study aimed to analyze the recovery period of the anodized 316L biomedical stainless steel (BSS) mini-implant through its implantation on femur of rabbit model. The 316L BSS mini-implant was modified by an electrochemical anodization approach with different voltages. The anodized samples were characterized via field-emission scanning electron microscopy, X-ray diffractometry, and X-ray photoelectron spectroscopy. The biocompatibility was assessed by cell culture assay. The anodized mini-implant was implanted on rabbit’s femur then evaluated histologically after 4 and 8 weeks. Analytical results indicated that the topography of the anodized mini-implant at 5 V for 5 min consisted of a dual (micro/nano) porous structure. Oxide film of Cr₂O₃ was formed on the surface of anodized mini-implant after anodizing with 5 V for 5 min. In vitro cell culture assay revealed that fibroblast cells (NIH-3T3) on the anodized samples were more firmly attached as compared with the control sample. Moreover, histological analysis demonstrated that the anodized mini-implant improved bone recovering at 4 weeks after implantation. Thus, this study suggests that the anodized 316L BSS mini-implant could be a potential choice as anchorage device for effective and efficient orthodontic treatment.

【 授权许可】

Unknown