Observational study: handgrip strength, body composition and diabetes mellitus

BMC Research Notes

Yukiko Wagatsuma¹  Chrispin Manda²  Joshua Gallagher³  Naomi Suda⁴ 

[1] Department of Clinical Trials and Clinical Epidemiology, Faculty of Medicine, University of Tsukuba;Department of Clinical Trials and Clinical Epidemiology, Graduate School of Comprehensive Human Sciences, University of Tsukuba;Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge;School of Medicine and Medical Science, University of Tsukuba;

关键词: Diabetes;    Handgrip strength;    Body composition;    Body mass index;    Fat free mass;   

DOI  :  10.1186/s13104-021-05731-4

来源: DOAJ

【 摘 要 】

Abstract Objective Previous studies have shown that relative handgrip strength, handgrip measure divided by body mass index (BMI), affects the future onset of diabetes and prediabetes. However, fat free mass (FFM) has been suggested to adjust for this effect better than BMI. In this study, we examined applicability of models that adjusted handgrip-diabetes relationship with either BMI or FFM. Results Of 1940 participants (56.2% male, average (SD) age, 57.2 [11.2] years), 267 (13.8%) had diabetes (DM) and 912 (47.0%) had prediabetes (pre-DM). The average handgrip measure for men was 40.0 kg (tertile measures, 37.4 kg and 42.5 kg) and for women 24.2 kg (tertile measures, 22.6 kg and 25.7 kg). Among both sexes, the percentage of people unaffected by DM or pre-DM was highest in the strong handgrip group and lowest in the weak handgrip group. Analysis using binary logistic models showed that an increase in handgrip measure was associated with a decrease in the chance of having either pre-DM or DM. This effect was detected by both BMI models and FFM models, even after adjustment for medical and lifestyle factors. Either or both should be used depending on the research aims, setting and methods.

【 授权许可】

Unknown