期刊论文详细信息
Frontiers in Neuroanatomy
Time for Radical Changes in Brain Stem Nomenclature—Applying the Lessons From Developmental Gene Patterns
Luis Puelles1  Charles Watson2  Caitlin Bartholomaeus3 
[1] Department of Human Anatomy and IMIB-Arrixaca Institute, School of Medicine, University of Murcia, Murcia, Spain;Neuroscience Research Australia, The University of New South Wales, Sydney, NSW, Australia;School of Biological Sciences, University of Western Australia, Perth, WA, Australia;
关键词: brain stem;    hindbrain;    midbrain;    isthmus;    rhombomeres;   
DOI  :  10.3389/fnana.2019.00010
来源: DOAJ
【 摘 要 】

The traditional subdivision of the brain stem into midbrain, pons, and medulla oblongata is based purely on the external appearance of the human brain stem. There is an urgent need to update the names of brain stem structures to be consistent with the discovery of rhomobomeric segmentation based on gene expression. The most important mistakes are the belief that the pons occupies the upper half of the hindbrain, the failure to recognize the isthmus as the first segment of the hindbrain, and the mistaken inclusion of diencephalic structures in the midbrain. The new nomenclature will apply to all mammals. This essay recommends a new brain stem nomenclature based on developmental gene expression, progeny analysis, and fate mapping. In addition, we have made comment on the names given to a number of internal brain stem structures and have offered alternatives where necessary.

【 授权许可】

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