Protocol for assessing and predicting acute respiratory decline in hospitalized patients

STAR Protocols

Louis T. Merriam¹  Jeremy R. DeGrado²  Justin D. Salciccioli²  Edy Y. Kim³  Conor P. Crowley⁴  Alisa A. Mueller⁴  Hibah Haider⁴  Tomoyoshi Tamura⁵ 

[1] Corresponding author;Harvard Medical School, Boston, MA 02115, USA;Department of Pharmacy, Brigham and Women’s Hospital, Boston, MA 02115 USA;Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, Boston, MA 02115, USA;Division of Rheumatology, Brigham and Women’s Hospital, Boston, MA 02115 USA;

关键词: Health Sciences;    Clinical Protocol;    Immunology;   

DOI  :  

来源: DOAJ

【 摘 要 】

Summary: This protocol aids both new and experienced researchers in designing retrospective clinical and translational studies of acute respiratory decline in hospitalized patients. This protocol addresses (1) the basics of respiratory failure and electronic health record research, (2) defining patient cohorts as “mild, progressive, or severe” instead of “ICU versus non-ICU”, (3) adapting physiological indices, and (4) using biomarker trends. We apply these approaches to inflammatory biomarkers in COVID-19, but this protocol can be applied to any progressive respiratory failure study.For complete details on the use and execution of this protocol, please refer to Mueller et al. (2020).

【 授权许可】

Unknown