Retrospective analysis of Vitek®2 performance compared to manual broth micro-dilution for colistin susceptibility testing of Acinetobacter baumanniicomplex isolates in South Africa

African Journal of Laboratory Medicine

Teena Thomas¹  Vuyolwethu Fadana²  Nina von Knorring² 

[1] and, Department Pathology, National Health Laboratory Services, Johannesburg;School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa;

关键词: acinetobacter;    colistin;    broth micro-dilution;    vitek®2;    antimicrobial susceptibility testing;   

DOI  :  10.4102/ajlm.v11i1.1597

来源: DOAJ

【 摘 要 】

The manual broth micro-dilution (mBMD) is the recommended reference method for colistin minimum inhibitory concentration determination; however, it is not as readily available in South Africa as the Vitek®2. This retrospective study compared the performance of Vitek®2 against mBMD in determining the colistin minimum inhibitory concentration of 337 extensively drug-resistant Acinetobacter baumannii complex isolates. Vitek®2 yielded a categorical agreement of 89%, an essential agreement of 56%, a major error rate of 8% and a very major error rate of 55%. The Vitek®2 is not an alternative to mBMD for colistin susceptibility testing.

【 授权许可】

Unknown