Purtscher-Like Retinopathy Associated with Atypical Hemolytic Uremic Syndrome

Türk Oftalmoloji Dergisi

Mesut Ayer¹  Savaş Öztürk²  Nilgün Solmaz²  Feyza Önder³  Melih Ustaoğlu⁴ 

[1] University of Health Sciences, Haseki Training and Research Hospital, Hematology Clinic, İstanbul, Turkey;University of Health Sciences, Haseki Training and Research Hospital, Nephrology Clinic, İstanbul, Turkey;University of Health Sciences, Haseki Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey;University of Health Sciences, Şişli Hamidiye Etfal Training and Research Hospital, Ophthalmology Clinic, İstanbul, Turkey;

关键词: Atypical hemolytic uremic syndrome;    Purtscher retinopathy;    Purtscher-like retinopathy;    thrombotic microangiopathy;    eculizumab;   

DOI  :  10.4274/tjo.66502

来源: DOAJ

【 摘 要 】

A 25-year-old woman presented with acute bilateral blurred vision and history of headache, dizziness, and syncope for three days. Her visual acuity was 20/60 in both eyes. Fundoscopy revealed multiple bilateral peripapillary yellow-white patches like cotton wool spots, intraretinal hemorrhages and macular edema. The patient was diagnosed with Purtscher-like retinopathy based on the retinal findings and lack of trauma history. She was urgently admitted to the nephrology clinic due to thrombotic microangiopathy findings (hemoglobinemia, thrombocytopenia, and acute renal failure). After excluding thrombotic microangiopathy, the patient was diagnosed with atypical hemolytic uremic syndrome (aHUS) with the clinical and laboratory findings. Eculizumab treatment was added to hemodialysis and plasmapheresis therapy. Three months after starting treatment, retinal lesions regressed and visual acuity increased to 20/20 in both eyes. To the best of our knowledge, this is the first reported case of Purtscher-like retinopathy associated with aHUS.

【 授权许可】

Unknown