期刊论文详细信息
Racionalʹnaâ Farmakoterapiâ v Kardiologii | |
INTERCHANGEABILITY OF MYOCARDIAL CYTOPROTECTORS IN PATIENTS WITH ISCHEMIC HEART DISEASE. DIFFICULT QUESTIONS –SIMPLE SOLUTIONS | |
Zh. M. Sizova1  | |
[1] Первый Московский государственный медицинский университет им. И.М.Сеченова; | |
关键词: ишемическая болезнь сердца; хроническая сердечная недостаточность; стенокардия; прекондиционирование; цитопротекция; триметазидин; оригинальный препарат; дженерик; фармакотерапия; | |
DOI : 10.1234/1819-6446-2013-2-183-187 | |
来源: DOAJ |
【 摘 要 】
Indications for myocardial cytoprotector, trimetazidine, in patients with ischemic heart disease are analyzed and justified according to evidence based medicine. Results of a multicenter randomized comparative KARDIOKANON study are discussed in terms of efficacy and tolerability of two variants of the complex 12-week treatment in patients with angina II-III functional class, based on the original and generic drugs. The study showed clinical equivalence of the generic DeprenormR (Canonpharma Production) to the original trimetazidine.
【 授权许可】
Unknown