A case-control study on the risk factors for hemorrhagic fever with renal syndrome

BMC Infectious Diseases

Jiankui Lu¹  Jing Lu²  Zhifeng Li³  Wenqi Shen³  Changjun Bao³  Weizhong Zhou³  Fengcai Zhu³  Jianli Hu³  Fenyang Tang³  Yuanfang Qin³  Xiaochen Wang³  Nan Zhang³  Liang Ying⁴  Haipeng Li⁴ 

[1] Department of Acute Infectious Disease Control and Prevention, Guanyun County Center for Disease Control and Prevention;Department of Acute Infectious Disease Control and Prevention, Haizhou County Center for Disease Control and Prevention;Department of Acute Infectious Disease Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention;Department of Acute Infectious Disease Control and Prevention, Lianyungang Municipal Center for Disease Control and Prevention;

关键词: Hemorrhagic fever with renal syndrome;    HFRS;    Case-control study;    Community-based;   

DOI  :  10.1186/s12879-020-4830-5

来源: DOAJ

【 摘 要 】

Abstract Background Hemorrhagic fever with renal syndrome (HFRS) is an endemic communicable disease in China, accounting for 90% of total reported cases worldwide. In this study, the authors want to investigate the risk factors for HFRS in recent years to provide the prevention and control advices. Methods A community-based, 1:2 matched case-control study was carried out to investigate the risk factors for HFRS. Cases were defined as laboratory-confirmed cases that tested positive for hantavirus-specific IgM antibodies. Two neighbourhood controls of each case were selected by sex, age and occupation. Standardized questionnaires were used to collect information and identify the risk factors for HFRS. Results Eighty-six matched pairs were investigated in the study. The median age of the cases was 55.0 years, 72.09% were male, and 73.26% were farmers. In the multivariate logistic regression analysis, cleaning spare room at home (OR = 3.310, 95%CI 1.335–8.210) was found to be risk factor for infection; storing food and crops properly (OR = 0.279 95%CI 0.097–0.804) provided protection from infection. Conclusion Storing food and crops properly seemed to be protective factor, which was important for HFRS prevention and control. More attention should be paid to promote comprehensive health education and behaviour change among high-risk populations in the HFRS endemic area.

【 授权许可】

Unknown