A Compact Multi-Distance DCS and Time Domain NIRS Hybrid System for Hemodynamic and Metabolic Measurements

Sensors

Lorenzo Spinelli¹  Alberto Tosi²  Mauro Buttafava²  Michele Lacerenza³  Caterina Amendola³  Davide Contini³  Alessandro Torricelli³ 

[1] Consiglio Nazionale delle Ricerche, Istituto di Fotonica e Nanotecnologie, piazza Leonardo da Vinci 32, 20133 Milan, Italy;Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, via Ponzio 34/5, 20133 Milan, Italy;Dipartimento di Fisica, Politecnico di Milano, piazza Leonardo da Vinci 32, 20133 Milan, Italy;

关键词: diffuse correlation spectroscopy;    time domain near infrared spectroscopy;    diffuse optics;   

DOI  :  10.3390/s21030870

来源: DOAJ

【 摘 要 】

In this work, we present a new multi-distance diffuse correlation spectroscopy (DCS) device integrated with a compact state-of-the-art time domain near infrared spectroscopy (TD-NIRS) device. The hybrid DCS and TD-NIRS system allows to retrieve information on blood flow, tissue oxygenation, and oxygen metabolic rate. The DCS device performances were estimated in terms of stability, repeatability, ability in retrieving variations of diffusion coefficient, influence of the tissue optical properties, effect of varying count rates and depth sensitivity. Crosstalk between DCS and TD-NIRS optical signals was also evaluated. Finally, in vivo experiments (venous and arterial cuff occlusions on the arm) were conducted to test the ability of the hybrid system in measuring blood flow variations.

【 授权许可】

Unknown