Similarities and Differences of CT Features between COVID-19 Pneumonia and Heart Failure

Cardiovascular Innovations and Applications

Zhenfei Fang, MD¹  Xinqun Hu, MD¹  Jia He, MD¹  Zhaowei Zhu, MD¹  Jianjun Tang, MD¹  Shi Tai, MD¹  Liang Tang, MD¹  Danyan Xu, MD¹  Shenghua Zhou, MD¹  Xiangping Chai, MD²  Qiming Hu, MD³  Yuzhi Wu, MD³ 

[1] Department of Cardiovascular Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China;Department of Emergency, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China;Department of Radiology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China;

关键词: computed tomography;    covid-19;    pneumonia;    heart failure;   

DOI  :  10.15212/CVIA.2021.0016

来源: DOAJ

【 摘 要 】

Aims: During the COVID-19 epidemic, chest computed tomography (CT) has been highly recommended for screening of patients with suspected COVID-19 because of an unclear contact history, overlapping clinical features, and an overwhelmed health system. However, there has not been a full comparison of CT for diagnosis of heart failure or COVID-19 pneumonia.Methods: Patients with heart failure (n=23) or COVID-19 pneumonia (n=23) and one patient with both diseases were retrospectively enrolled. Clinical information and chest CT images were obtained and analyzed.Results: There was no difference in ground-glass opacity, consolidation, crazy paving pattern, the lobes affected, and septal thickening between heart failure and COVID-19 pneumonia. However, a less rounded morphology (4% vs. 70%, P=0.00092), more peribronchovascular thickening (70% vs. 35%, P=0.018) and fissural thickening (43% vs. 4%, P=0.002), and less peripheral distribution (30% vs. 87%, P=0.00085) were found in the heart failure group than in the COVID-19 group. Importantly, there were also more patients with upper pulmonary vein enlargement (61% vs. 4%, P=0.00087), subpleural effusion (50% vs. 0%, P=0.00058), and cardiac enlargement (61% vs. 4%, P=0.00075) in the heart failure group than in the COVID-19 group. Besides, more fibrous lesions were found in the COVID-19 group, although there was no statistical difference (22% vs. 4%, P=0.080).Conclusions: Although there is some overlap of CT features between heart failure and COVID-19, CT is still a useful tool for differentiating COVID-19 pneumonia.

【 授权许可】

Unknown