Chemical and Photochemical Synthesis of Substituted Dihydro-thieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones and Tetrahydro-dithieno[2,3-b:2',3'-d]thieno[2'',3''c:2'',3''c’]diquinolin-6,14-dione

Molecules

关键词: Substituted dihydrothieno[2';    3':4;    5]thieno[2;    3-c]quinolin-6-ones;    Tetra- hydrodithieno[2;    3-b:2';    3'-d]thieno[2'';    3''c:2'';    3''c’]diquinolin-6;    14-dione;    Synthesis;    Photo- chemical synthesis;    DNA Intercalators;    Anticancer therapy.;   

DOI  :  10.3390/10010279

来源: DOAJ

【 摘 要 】

Some new substituted dihydrothieno[2',3':4,5]thieno[2,3-c]quinolin-6-ones 9- 12 and tetrahydrodithieno[2,3-b: 2',3'-d]thieno[2'',3''-c:2'',3''-c’]diquinolin-6,14-dione (17) were prepared from the corresponding new anilides 5-8 and from the corresponding dianilide 15, respectively, by a multistep combination of chemical and photochemical reactions. All the prepared compounds are of particular interest because they might serve as DNA intercalators in anticancer therapy.

【 授权许可】

Unknown