Body composition determinants of radiation dose during abdominopelvic CT

Insights into Imaging

Patrick D. McLaughlin¹  Joseph A. Eustace²  Siobhán B. O’Neill³  Niamh Moore³  Owen J. O’Connor⁴  Charles Sullivan⁴  Karl James⁴  Richard G. Kavanagh⁴  Michael M. Maher⁴  Kevin P. Murphy⁴  Faimee E. Chan⁴  Maria Twomey⁴  Sebastian R. McWilliams⁴  Liam Chawke⁴ 

[1] Department of Emergency and Trauma Radiology, Vancouver General Hospital;Department of Nephrology, Cork University Hospital;Department of Radiology, Cork University Hospital;Department of Radiology, University College Cork;

关键词: Tomography, X-ray computed;    Radiation dosage;    Intra-abdominal fat;    Muscle, Skeletal;    Body mass index;   

DOI  :  10.1007/s13244-017-0577-y

来源: DOAJ

【 摘 要 】

Abstract Objectives We designed a prospective study to investigate the in-vivo relationship between abdominal body composition and radiation exposure to determine the strongest body composition predictor of dose length product (DLP) at CT. Methods Following institutional review board approval, quantitative analysis was performed prospectively on 239 consecutive patients who underwent abdominopelvic CT. DLP, BMI, volumes of abdominal adipose tissue, muscle, bone and solid organs were recorded. Results All measured body composition parameters correlated positively with DLP. Linear regression (R2 = 0.77) revealed that total adipose volume was the strongest predictor of radiation exposure [B (95% CI) = 0.027(0.024–0.030), t=23.068, p < 0.001]. Stepwise linear regression using DLP as the dependent and BMI and total adipose tissue as independent variables demonstrated that total adipose tissue is more predictive of DLP than BMI [B (95% CI) = 16.045 (11.337-20.752), t=6.681, p < 0.001]. Conclusions The volume of adipose tissue was the strongest predictor of radiation exposure in our cohort. Main message • Individual body composition variables correlate with DLP at abdominopelvic CT. • Total abdominal adipose tissue is the strongest predictor of radiation exposure. • Muscle volume is also a significant but weaker predictor of DLP.

【 授权许可】

Unknown