Implementing the right care in the right place at the right time for non-alcoholic fatty liver disease (NAFLD-RRR study): a study protocol for a community care pathway for people with type 2 diabetes

BMC Health Services Research

Steven McPhail¹  Anthony Russell²  Elizabeth E. Powell³  Kelly L. Hayward³  Melanie Aikebuse³  Lucy Gracen³  Patricia C. Valery³  James O’Beirne⁴  Suzanne Williams⁵  Katharine M. Irvine⁶ 

[1]Australian Centre for Health Services Innovation School of Public Health, Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT)

[2]Centre for Health Services Research, Faculty of Medicine, The University of Queensland

[3]Centre for Liver Disease Research, Faculty of Medicine, Translational Research Institute, The University of Queensland

[4]Department of Gastroenterology and Hepatology, Sunshine Coast University Hospital

[5]Inala Primary Care General Practice

[6]Mater Research, Translational Research Institute

关键词: Cirrhosis;    Diabetes complications;    Patient care;    Risk assessment;    Delivery of health care;    Integrated;   

DOI  :  10.1186/s12913-022-07808-7

来源: DOAJ

【 摘 要 】

Abstract Background Non-alcoholic fatty liver disease (NAFLD) is an emerging epidemic that affects approximately half of all people with type 2 diabetes. Those with type 2 diabetes are a high-risk NAFLD subgroup because of their increased risk of clinically significant liver-related outcomes from NAFLD which include hepatocellular carcinoma, cirrhosis-related complications and liver disease mortality. They may benefit from early detection of disease as this would allow at risk patients to access hepatocellular carcinoma surveillance, emerging drug trials for NAFLD and specialist hepatology care prior to emergence of liver-related complications. Methods This is a prospective cohort study aimed at incorporating and assessing a community care pathway for liver fibrosis screening into routine care for type 2 diabetes. Patients undergo a point of care assessment of hepatic steatosis and stiffness using FibroScan at the time of the routine diabetes appointment or when attending the clinic for blood tests in preparation for this appointment. Discussion We propose that implementation of a community-based NAFLD diagnosis, risk-stratification, and referral pathway for people with type 2 diabetes is feasible, will provide earlier, targeted detection of advanced fibrosis, and reduce unnecessary referrals to hepatology outpatients for fibrosis risk assessment. Our study will provide important information about the feasibility of establishing a NAFLD pathway for people with type 2 diabetes in primary care. Ultimately, our findings will help direct spending and resource allocation for NAFLD in a high-risk population. Regular evaluation by stakeholders during implementation will help to create a reliable and sustainable community care pathway and establish a perpetual cycle of learning in primary care. Trial registration ANZCTR, ACTRN12621000330842 . Registered 23 March 2021.

【 授权许可】

Unknown