Fourier Ptychographic Microscopy via Alternating Direction Method of Multipliers

Cells

Siqi Wang¹  Zhuoqun Zhang²  An Pan³  Caiwen Ma³  Aiye Wang³  Baoli Yao³ 

[1] Centre Énergie Matériaux Télécommunications, Institut National de la Recherche Scientifique, Varennes, QC J3X 1S2, Canada;Department of Electronic and Electrical Engineering, University of Sheffield, Sheffield S1 3JD, UK;Xi’an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi’an 710119, China;

关键词: Fourier ptychographic microscopy;    alternating-direction method of multipliers;    phase retrieval;    computational imaging;    digital pathology;    whole slide imaging;   

DOI  :  10.3390/cells11091512

来源: DOAJ

【 摘 要 】

Fourier ptychographic microscopy (FPM) has risen as a promising computational imaging technique that breaks the trade-off between high resolution and large field of view (FOV). Its reconstruction is normally formulated as a blind phase retrieval problem, where both the object and probe have to be recovered from phaseless measured data. However, the stability and reconstruction quality may dramatically deteriorate in the presence of noise interference. Herein, we utilized the concept of alternating direction method of multipliers (ADMM) to solve this problem (termed ADMM-FPM) by breaking it into multiple subproblems, each of which may be easier to deal with. We compared its performance against existing algorithms in both simulated and practical FPM platform. It is found that ADMM-FPM method belongs to a global optimization algorithm with a high degree of parallelism and thus results in a more stable and robust phase recovery under noisy conditions. We anticipate that ADMM will rekindle interest in FPM as more modifications and innovations are implemented in the future.

【 授权许可】

Unknown