Point prevalence survey of antimicrobial use in three hospitals in North-Eastern Tanzania

Antimicrobial Resistance and Infection Control

Stephen E. Mshana¹  Elise F. Mouw²  Quirijn de Mast²  Jaffu O. Chilongola³  Pius G. Horumpende³  Blandina T. Mmbaga³ 

[1] Catholic University of Health and Allied Sciences (CUHAS);Department of Internal Medicine, Radboudumc Center for Infectious Diseases, Radboud University Medical Centre;Kilimanjaro Christian Medical University College;

关键词: Antibiotic prescription;    Antibiotic stewardship;    Point prevalence survey;    Antimicrobial resistance;    Tanzania;   

DOI  :  10.1186/s13756-020-00809-3

来源: DOAJ

【 摘 要 】

Abstract Background Antimicrobial resistance (AMR) is one of the most urgent global health threats with low-resource countries being disproportionately affected. Targeted interventions require insight in antibiotic prescription practices. A point prevalence survey (PPS) is a well-known tool to get insight in antibiotic dispensing practices in hospitals and identify areas for improvement. Here, we describe the results of a PPS performed in a tertiary, regional and district hospital in Kilimanjaro region in Tanzania. Methods A PPS was performed in the Kilimanjaro Christian Medical Centre (KCMC; tertiary hospital), Mawenzi (regional) and St. Joseph (district) hospital in November and December 2016. Antibiotic use in all patients admitted more than 24 h and those undergoing surgery was recorded. All clinical wards were included except the pediatrics. Data from a single ward were collected on the same day. Results A total of 399 patients were included in the PPS: 232 patients from KCMC, 94 from Mawenzi hospital and 73 patients from St. Joseph hospital. Overall prevalence of antibiotic use was 44.0%: 38% in KCMC, 59% in Mawenzi and 63% in St. Joseph. Ceftriaxone (n = 94, 29.8%), metronidazole (n = 79, 23.9%) and other antibiotics belonging to the penicillin class (n = 89, 28.3%) were most commonly prescribed. Antibiotics prescribed for surgical prophylaxis were continued for more than 3 days in 57% of cases. Conclusion Our study shows a rate of broad-spectrum antibiotic use in Tanzanian hospitals and prolonged surgical antibiotic prophylaxis being a common practice. PPS is an important tool to improve future antibiotic use in Tanzania hospitals.

【 授权许可】

Unknown