Effect of medium with moderate temperature on patient's body temperature during percutaneous endoscopic lumbar discectomy

Journal of Orthopaedic Surgery and Research

Lidong Zhang¹  Rui Zhao¹  Bin Pan¹  Fuchao Chu¹  Xiaona Liu¹  Huilin Yu¹  Feng Yuan¹  Maji Sun¹  Jibin Wu¹ 

[1] Department of Spine Surgery, The Affiliated Hospital of Xuzhou Medical University;

关键词: PELD;    Hypothermia;    Inflammatory cytokines;    Inflammatory reaction;   

DOI  :  10.1186/s13018-022-03226-x

来源: DOAJ

【 摘 要 】

Abstract Purpose To explore the influence of irrigating fluid at different temperatures on patients' body temperature and local inflammatory mediators during spinal endoscopy. Methods 110 cases of intervertebral foramen surgery in our hospital from January 2019 to October 2021 were randomly divided into control group and observation group. Operations of both groups were performed by the same experienced chief physician. The observation group was irrigated with 37 °C constant temperature saline, while the control group was irrigated at room temperature. The effect was evaluated by monitoring the intraoperative temperature, postoperative VAS score and the levels of inflammatory factors, such as TNF-α, IL-1, IL-6 and IL-10 in drainage fluid. Results After 30 min of operation, overall temperature of the control group dropped significantly, and 50 cases (90.9%) had hypothermia, P < 0.05. There was no significant difference in preoperative VAS score between the two groups P > 0.05. The VAS score of observation group was significantly lower than that of control group at 6 h and 1 month after operation, P < 0.05. At 0, 3 and 6 h after operation, the values of TNF-α, IL-1, IL-6 and IL-10 in the observation group were significantly lower than those in the control group (P < 0.05). Conclusions Isothermal flushing solution can reduce the incidence of hypothermia and effectively alleviate local inflammatory reaction.

【 授权许可】

Unknown