Three-Component Reactions of 3-Arylidene-3H-Indolium Salts, Isocyanides and Amines

Molecules

AlexandraS. Golubenkova¹  HungM. Nguyen¹  NikitaE. Golantsov¹  LeonidG. Voskressensky¹  VictorB. Rybakov² 

[1] Department of Organic Chemistry, Faculty of Science, Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., 117198 Moscow, Russia;Faculty of Chemistry, Lomonosov Moscow State University, 1-3 Leninskiye Gory, 119991 Moscow, Russia;

关键词: multicomponent reactions;    isocyanides;    carbenium ions;    indoles;    imidamides;    imidazolones;   

DOI  :  10.3390/molecules26092402

来源: DOAJ

【 摘 要 】

A multicomponent reaction of isocyanides with aryl(indol-3-yl)methylium salts and amines has been found. A series of aryl(indol-3-yl)acetimidamides was obtained in up to 96% yields. In the case of ethyl isocyanoacetate, the reaction is followed by cyclization to form 3,5-dihydro-4H-imidazol-4-one derivatives.

【 授权许可】

Unknown