The synthesis, antimicrobial activity and docking studiesof 6-(1H-benzimidazol-2-yl)-5-methylthieno[2,3-d]pyrimidin-4(3H)-ones with acetamide and 1,2,4-oxadiazol-5-ylmethyl substituents

Журнал органічної та фармацевтичної хімії

Hanna I. Severina¹  Oleksandr V. Borysov²  Vitaliy S. Vlasov³  Victoriya A. Georgiyants⁴  Sergiy V. Vlasov⁴  Sergiy M. Kovalenko⁴  Tetiana P. Osolodchenko⁵ 

[1] Enamine Ltd., Ukraine;Institute of Organic Chemistry of the National Academy of Sciences of Ukraine;Mechnikov Institute of Microbiology and Immunology of the National Academy of Medical Sciences of Ukraine, Ukraine;National University of Pharmacy of the Ministry of Health of Ukraine, Ukraine;V. N. Karazin Kharkiv National University, Ukraine;

关键词: thiophene;    pyrimidine;    alkylation;    antimicrobial agents;    inhibitors;    molecular docking;   

DOI  :  https://doi.org/10.24959/ophcj.21.240775

来源: DOAJ

【 授权许可】

Unknown