Holmes Tremor due to Artery of Percheron Infarct: Clinical Case and Treatment Using Deep Brain Stimulation of the Vim and ZI Targets

Tremor and Other Hyperkinetic Movements

Sarah A. O’Shea¹  Mitchell Elkind²  Seth L. Pullman²  Blair Ford² 

[1] Department of Neurology, Boston University School of Medicine, Boston University, Boston, MA, USA;Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA;

关键词: deep brain stimulation;    holmes tremor;    tremor;    neurostimulation;   

DOI  :  10.7916/tohm.v0.732

来源: DOAJ

【 摘 要 】

Background: Holmes tremor (HT) arises from disruption of the cerebellothalamocortical pathways. A lesion can interrupt the projection at any point, resulting in this tremor. We describe a case of HT due to the rare artery of Percheron infarct and its successful treatment using deep brain stimulation. Case report: A 62-year-old woman with a right medial cerebral peduncle and bilateral thalamic stroke developed HT. Ventral intermediate nucleus (Vim) zona incerta (ZI) deep brain stimulation (DBS) surgery was performed, with improvement in her tremor. Discussion: Our case supports the theory that the more caudal ZI target in combination with Vim is beneficial in treating poorly DBS-responsive tremors such as HT.

【 授权许可】

Unknown