The toxicological mechanisms and detoxification of depleted uranium exposure

Environmental Health and Preventive Medicine

Wei He¹  Hai-Bo Wang¹  Yong-Chao Yue¹  Ming-Hua Li¹  Bang-Le Zhang² 

[1] Department of Chemistry, School of Pharmacy, Fourth Military Medical University;Department of Pharmaceutics, School of Pharmacy, Fourth Military Medical University;

关键词: Depleted uranium;    Toxicity;    Decorporation;    Chelating agents;   

DOI  :  10.1186/s12199-018-0706-3

来源: DOAJ

【 摘 要 】

Abstract Depleted uranium (DU) has been widely applied in industrial and military activities, and is often obtained from producing fuel for nuclear reactors. DU may be released into the environment, polluting air, soil, and water, and is considered to exert both radiological and chemical toxicity. In humans and animals, DU can induce multiple health effects, such as renal tubular necrosis and bone malignancies. This review summarizes the known information on DU’s routes of entry, mechanisms of toxicity, and health effects. In addition, we survey the chelating agents used in ameliorating DU toxicity.

【 授权许可】

Unknown