Ruptured Hepatocellular Carcinoma: Current Status of Research

Frontiers in Oncology

Mingyu Zhang¹  Bixiang Zhang²  Peng Zhu²  Elijah Ndhlovu²  Xiaoping Chen²  Feng Xia² 

[1] Department of Digestive Medicine. Tongji Hospital of Tongji Medical College in Huazhong University of Science and Technology, Wuhan, China;Department of Hepatic Surgery Center, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China;

关键词: hepatocellular carcinoma;    spontaneous rupture;    mechanism;    diagnosis;    treatment;   

DOI  :  10.3389/fonc.2022.848903

来源: DOAJ

【 摘 要 】

BackgroundRuptured hepatocellular carcinoma (rHCC) is considered a rare and life-threatening manifestation; when it happens, it often requires acute and positive intervention. At present, the mechanism of rHCC development is gradually being understood while there are many kinds of rHCC treatment. From our clinical observation, the prognosis of rHCC patients is not as poor as it is currently believed. It may not be appropriate to include all patients with rHCC in T4.Main BodyThe incidence of ruptured hepatocellular carcinoma is now rising. Especially in the Asian region, it can even reach 10% – 15%. The most common symptom of HCC rupture is abdominal pain, and there are now a variety of treatments for hepatocellular carcinoma rupture. With aggressive treatment, rHCC patients can also achieve a better prognosis. The patient’s condition varies on admission, so the treatment methods will also be different. It is critical to identify prognostic factors simultaneously, and rHCC can be effectively managed by focusing on important prognostic factors.ConclusionA review was carried out to analyze diagnosis, mechanism, treatment, and prognostic risk factors on this disease condition during the current situation; it is hoped that it will provide better guidance for clinicians. Moreover, patients with rHCC were managed hierarchically to prolong their prognosis.

【 授权许可】

Unknown