Cost analysis of negative-pressure wound therapy versus standard treatment of acute conflict-related extremity wounds within a randomized controlled trial

World Journal of Emergency Surgery

Rawand Haweizy¹  Jonas Malmstedt²  Andreas Älgå²  Birger C. Forsberg³  Johan von Schreeb³  Jenny Löfgren⁴  Khaldoon Bashaireh⁵  Sidney Wong⁶ 

[1] College of Medicine, Hawler Medical University;Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet;Department of Global Public Health, Karolinska Institutet;Department of Molecular Medicine and Surgery, Karolinska Institutet;Department of Special Surgery, Jordan University of Science and Technology;Médecins Sans Frontières, Operational Centre Amsterdam;

关键词: Trauma;    Armed conflict;    Wounds;    Cost analysis;   

DOI  :  10.1186/s13017-022-00415-1

来源: DOAJ

【 摘 要 】

Abstract Background Clinical outcomes after negative-pressure wound therapy (NPWT) and standard treatment of conflict-related extremity wounds are similar. In resource-limited settings, cost affects the choice of treatment. We aimed to estimate treatment-related costs of NPWT in comparison with standard treatment for conflict-related extremity wounds. Methods We derived outcome data from a randomized, controlled superiority trial that enrolled adult (≥ 18 years) patients with acute (≤ 72 h) conflict-related extremity wounds at two civilian hospitals in Jordan and Iraq. Primary endpoint was mean treatment-related healthcare costs (adjusted to 2019 US dollars). Results Patients were enrolled from June 9, 2015, to October 24, 2018. A total of 165 patients (155 men [93.9%]; 10 women [6.1%]; and median [IQR] age, 28 [21–34] years) were included in the analysis. The cost per patient treated with NPWT was $142 above that of standard treatment. Overall, results were robust in a sensitivity analysis. Conclusions With similar clinical outcomes compared to standard care, our results do not support the use of NPWT in routine treatment of conflict-related extremity wounds at civilian hospitals in resource scarce settings. Trial registration NCT02444598.

【 授权许可】

Unknown