Vesicles in Multiple Shapes: Fine-Tuning Polymersomes’ Shape and Stability by Setting Membrane Hydrophobicity

Polymers

Wolfgang Meier¹  Jens Gaitzsch¹  Eloise Morecroft²  Lea Messager³ 

[1] Departement of Chemistry, University of Basel, Mattenstrasse 24a, BPR1096, 4058 Basel, Switzerland;Institute of Chemical Biology, Exhibition Road, London SW7 2AZ, UK;LAGEP-Université Claude Bernard Lyon 1, 43 Boulevard du 11 novembre 1918, Bâtiment CPE-308G, M69622 Villeurbanne Cedex, France;

关键词: self-assembly;    polymersomes;    temperature-sensitivity;    ATRP;   

DOI  :  10.3390/polym9100483

来源: DOAJ

【 摘 要 】

Amphiphilic block-copolymers are known to self-assemble into micelles and vesicles. In this paper, we discuss the multiple options between and beyond these boundaries using amphiphilic AB diblock and ABC triblock copolymers. We adjust the final structure reached by the composition of the mixture, by the preparation temperature, and by varying the time-scale of formation. This leads to the formation of vesicles and micelles, but also internal micelles in larger sheets, lamellar vesicles, and closed tubes, thus broadening the amount of self-assembly structures available and deepening our understanding of them.

【 授权许可】

Unknown