Cortical thickness of the tibial diaphysis reveals age- and sex-related characteristics between non-obese healthy young and elderly subjects depending on the tibial regions

Journal of Experimental Orthopaedics

Yoshio Koga¹  Hiroshi Koga²  Hiroyuki Kawashima²  Ryota Katsumi²  Keiichiro Someya²  Osamu Tanifuji²  Sho Hokari²  Keisuke Maeda²  Tomoharu Mochizuki²  Yusuke Morise³  Koichi Kobayashi⁴  Makoto Sakamoto⁴ 

[1] Department of Orthopedic Surgery, Nioji Onsen Hospital;Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Science;Graduate School of Science and Technology, Niigata University;School of Health Sciences, Faculty of Medicine, Niigata University;

关键词: Age;    Sex;    Cortical bone;    Tibia;   

DOI  :  10.1186/s40634-020-00297-9

来源: DOAJ

【 摘 要 】

Abstract Purpose This study aimed to evaluate the age- and sex-related characteristics in cortical thickness of the tibial diaphysis between non-obese healthy young and elderly subjects as reference data. Methods The study investigated 31 young subjects (12 men and 19 women; mean age, 25 ± 8 years) and 54 elderly subjects (29 men and 25 women; mean age, 70 ± 6 years). Three-dimensional estimated cortical thickness of the tibial diaphysis was automatically calculated for 5000–9000 measurement points using the high-resolution cortical thickness measurement from clinical computed tomography data. In 12 assessment regions created by combining three heights (proximal, central, and distal diaphysis) and four areas of the axial plane at 90° (medial, anterior, lateral, and posterior areas) in the tibial coordinate system, the standardized thickness was assessed using the tibial length. Results As structural characteristics, there were no differences in the medial and lateral thicknesses, while the anterior thickness was greater than the posterior thickness in all groups. The sex-related difference was not shown. As an age-related difference, elderly subjects showed greater or lesser cortical thickness than the young subjects, depending on the regions of the tibia. Conclusions Cortical thickness was different depending on sex, age, and regions in the tibia. The results of this study are of clinical relevance as reference points to clarify the causes of various pathological conditions for diseases. Level of evidence Level 3.

【 授权许可】

Unknown