Кардиоваскулярная терапия и профилактика | |
Cardioselective beta-adrenoblocker bisoprolol in treating hypertensive patients with heart failure | |
A. N. Britov1  | |
[1] State Research Center for Preventive Medicine, Ministry of Health of The Russian Federation, Moscow; | |
关键词: arterial hypertension; heart failure; diabetes mellitus; beta-adrenoblockers; bisoprolol; | |
DOI : | |
来源: DOAJ |
【 摘 要 】
The article is devoted to the role of modern beta-adrenoblockers (BB) in arterial hypertension (AH) treatment. Their indications include not only AH, but also coronary heart disease, heart failure (HF), and some cardiac arrhythmias. At present, it is widely accepted that BB are important in HF treatment: they decrease the negative effects of sympathic myocardial stimulation – myocardial overload, hypertrophy, fibrosis, and apoptosis. Beta-1 antagonist, bisoprolol, is a highly cardioselective agent. Therefore, it is often used in patients with AH and HF. This medication does not provoke hypoglycemia in diabetic individuals, or require oral anti-diabetic medication dosage correction. Concor® can be successfully combined with other medications, to effectively decrease cardiovascular morbidity and mortality
【 授权许可】
Unknown