THROMBOCYTOPENIA IN THE STRUCTURE OF HEMATOLOGICAL DISORDERS IN PATIENTS OF A MULTIPROFILE HOSPITAL AND POSSIBLE WAYS TO OPTIMIZE ITS EVALUATION

Медицинский совет

A. A. Sapegin¹  T. V. Vavilova¹  V. A. Kashchenko²  S. N. Semigolovskii³  S. Yu. Semigolovskii³ 

[1] Sankt-Petersburg State University.;Almazov’ National Medical Research Centre.;Sokolov’ Hospital №122 of Federal Medical and Biological Agency;

关键词: thrombocytopenia;    heparin-induced thrombocytopenia (hit);    drug-induced thrombocytopenia;    heparins;    immunodiagnostics;    thrombosis;    the original «rule» of hit diagnostics «100-5-100».;   

DOI  :  10.21518/2079-701X-2017-20-14-19

来源: DOAJ

【 摘 要 】

Analysis of the prevalence of thrombocytopenia in a multidisciplinary hospital, where it is treated about 25,000 patients a year, shows that from 1.15% to 1.45% of patients have threat reduction platelets less than 100x109/l. 40,2% of them (on average, 127 people per year) receive heparin and can potentially be seen as patients that are suspected to heparin-induced thrombocytopenia (HIT). Timely identification of such patients, the use of two rules – 4T and «100–5—100» allows you not to miss the patient with the development of HIT, time to switch to alternative anticoagulants and, if necessary, to stop the flushing of venous catheters with heparin solution. This tactic allows to reduce the number of patients, receiving heparin and thrombocytopenia below 100 х 109/l, almost 3 times as took place among hospitalized and patients in intensive care units in 3 years of using the mentioned tactics.

【 授权许可】

Unknown