Journal of Global Antimicrobial Resistance | |
Prospective infection surveillance and systematic screening for vancomycin-resistant enterococci in hematologic and oncologic patients – findings of a German tertiary care center | |
Christian Koenecke1  Felicitas Thol1  Gernot Beutel1  Dirk Schlüter2  Patrick Chhatwal2  Stefan Ziesing2  Franz-Christoph Bange2  Claas Baier2  Ella Ebadi2  | |
[1] Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School (MHH), Hannover, Germany;Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School (MHH), Hannover, Germany; | |
关键词: Vancomycin-resistant enterococci; intestinal colonization; infection; surveillance; screening; hematology and oncology; | |
DOI : | |
来源: DOAJ |
【 摘 要 】
Introduction: Vancomycin-resistant enterococci (VRE) are emerging multidrug-resistant bacteria. They can cause serious nosocomial infections, especially in immunocompromised patients. Objectives and methods: In this study, we aimed to determine the burden of intestinal VRE colonization and clinically relevant infection in adult hematologic and oncologic patients at a tertiary care clinic in Germany based on prospective infection surveillance and an active screening program. Results: In a 12 month period, 132 of 555 patients had intestinal VRE-colonization (23.8%) and four patients (0.7% of the entire cohort, and 3.0% of those colonized with VRE) developed a nosocomial infection with VRE. Conclusions: The prospective surveillance and active screening for VRE was very useful to determine the true ratio of intestinal colonization to infection and thus helps to shape infection control management.
【 授权许可】
Unknown