Prospective infection surveillance and systematic screening for vancomycin-resistant enterococci in hematologic and oncologic patients – findings of a German tertiary care center

Journal of Global Antimicrobial Resistance

Christian Koenecke¹  Felicitas Thol¹  Gernot Beutel¹  Dirk Schlüter²  Patrick Chhatwal²  Stefan Ziesing²  Franz-Christoph Bange²  Claas Baier²  Ella Ebadi² 

[1] Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School (MHH), Hannover, Germany;Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School (MHH), Hannover, Germany;

关键词: Vancomycin-resistant enterococci;    intestinal colonization;    infection;    surveillance;    screening;    hematology and oncology;   

DOI  :  

来源: DOAJ

【 摘 要 】

Introduction: Vancomycin-resistant enterococci (VRE) are emerging multidrug-resistant bacteria. They can cause serious nosocomial infections, especially in immunocompromised patients. Objectives and methods: In this study, we aimed to determine the burden of intestinal VRE colonization and clinically relevant infection in adult hematologic and oncologic patients at a tertiary care clinic in Germany based on prospective infection surveillance and an active screening program. Results: In a 12 month period, 132 of 555 patients had intestinal VRE-colonization (23.8%) and four patients (0.7% of the entire cohort, and 3.0% of those colonized with VRE) developed a nosocomial infection with VRE. Conclusions: The prospective surveillance and active screening for VRE was very useful to determine the true ratio of intestinal colonization to infection and thus helps to shape infection control management.

【 授权许可】

Unknown