A New Nomogram Based on Early Postoperative NLR for Predicting Infectious Complications After Gastrectomy

Cancer Management and Research

关键词: gastrectomy;    infectious complication;    nomogram;    prediction;    risk model;   

DOI  :  

来源: DOAJ

【 摘 要 】

Chen Wang, Han-zhang Huang, Yu He, Yu-jun Yu, Qing-miao Zhou, Rong-jian Wang, Jian-bo He, Shao-liang Han Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, People’s Republic of ChinaCorrespondence: Shao-liang HanDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, People’s Republic of ChinaTel [phone]Fax [phone]Email [e-mail]: Our study aimed to construct a visible model to evaluate the risk of infectious complications after gastrectomy.Methods: The clinical data of 856 patients who underwent gastrectomy were used to retrieve medical records. Univariate and multivariate analyses were performed to correlate early postoperative NLR and operative variables with postoperative complications, and the construction of the nomogram was based on logistic regression. The concordance index and receiver operating characteristic curves were used to evaluate the model performance.Results: The postoperative infectious and noninfectious complication rates after gastrectomy were 18.5% (158/856 cases) and 12.3% (105/856 cases) respectively. Postoperative NLR (within 24 h) independently predicted the development of postoperative infectious complication. Multivariate analysis revealed that age, diabetes, body mass index (BMI), intraoperative blood transfusion and postoperative NLR were independent risk factors. The nomogram model showed a good performance in terms of predicting infectious complications after gastrectomy (concordance index=0.718).Conclusion: Age, diabetes, BMI, intraoperative blood transfusion and postoperative NLR were independent risk factors of postoperative infectious complications after gastrectomy, and a novel nomogram based on these results can be used to predict postoperative infection and has the advantages of simple application and easy access.Keywords: gastrectomy, infectious complication, nomogram, prediction, risk model

【 授权许可】

Unknown