Association of Alcohol and Tobacco Consumption with Depression Severity in the Oldest Old. Results from the Age Different Old Age Cohort Platform

International Journal of Environmental Research and Public Health

Matthias C. Angermeyer¹  André Hajek²  Hans-Helmut König²  Kathrin Heser³  Michael Wagner³  Martin Scherer⁴  Hendrik van den Bussche⁴  Wolfgang Maier⁵  Birgitt Wiese⁶  Janine Quittschalle⁷  Alexander Pabst⁷  Melanie Luppa⁷  Margrit Löbner⁷  Steffi G. Riedel-Heller⁷ 

[1] Center for Public Mental Health, 3482 Gösing am Wagram, Austria;Department of Health Economics and Health Services Research, Hamburg Center for Health Economics, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany;Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, 53127 Bonn, Germany;Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany;German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany;Institute for General Practice, Hannover Medical School, 30625 Hannover, Germany;Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, 04103 Leipzig, Germany;

关键词: depression;    lifestyle factors;    old age;    gender differences;   

DOI  :  10.3390/ijerph18157959

来源: DOAJ

【 摘 要 】

This study aimed to examine the association of alcohol and tobacco use with severity of depression in older age. Analyses were performed on a pooled data set (n = 3724) from two German old-age cohort studies (LEILA 75+, 6 follow-ups and AgeCoDe/AgeQualiDe, 9 follow-ups). Depressive symptoms were assessed via two screening scales for depression (CES-D and GDS-15) which were harmonized for pooled analysis. A mixed-effects linear regression model for the total sample and additional stratified models for men and women were used. Smoking at baseline was significantly associated with a higher level of depression severity (β = 0.142, 95% CI: 0.051–0.233, p = 0.002), whereas drinking was significantly associated with a decreased level of depression (β = −0.069, 95% CI: −0.119–−0.021, p = 0.005). Concurrent substance use at baseline increased longitudinal depression severity (β = 0.193, 95% CI: 0.011–0.375, p = 0.037). Analyses stratified by gender showed a significant inverse association between drinking and depressive symptoms in men (β = −0.138, 95% CI: −0.231–−0.045, p = 0.004), but not in women (β = −0.060, 95% CI: −0.120–0.001, p = 0.052). Given the burden of major depression, it is important that health care providers, especially primary care physicians, assess and monitor lifestyle factors, even at older ages.

【 授权许可】

Unknown