Wiping out MRSA: effect of introducing a universal disinfection wipe in a large UK teaching hospital

Antimicrobial Resistance and Infection Control

Craig W. Bradley¹  Kerry L. Holden¹  Martyn A. C. Wilkinson²  Mark I. Garvey²  Elisabeth Holden² 

[1] Gloucestershire Hospital’s NHS Foundation Trust, Gloucester Royal Hospital;University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital Birmingham;

关键词: Meticillin-resistant Staphylococcus aureus;    MRSA bacteraemias;    MRSA acquisitions;    Disinfection wipes;   

DOI  :  10.1186/s13756-018-0445-7

来源: DOAJ

【 摘 要 】

Abstract Background Contamination of the inanimate environment around patients constitutes an important reservoir of MRSA. Here we describe the effect of introducing a universal disinfection wipe in all wards on the rates of MRSA acquisitions and bacteraemias across a large UK teaching hospital. Methods A segmented Poisson regression model was used to detect any significant changes in the monthly numbers per 100,000 bed days of MRSA acquisitions and bacteraemias from April 2013 - December 2017 across QEHB. Results From April 2013 to April 2016, cleaning of ward areas and multi-use patient equipment by nursing staff consisted of a two-wipe system. Firstly, a detergent wipe was used, which was followed by a disinfection step using an alcohol wipe. In May 2016, QEHB discontinued the use of a two-wipe system for cleaning and changed to a one wipe system utilising a combined cleaning and disinfection wipe containing a quaternary ammonium compound. The segmented Poisson regression model demonstrated that the rate of MRSA acquisition/100,000 patient bed days was affected by the introduction of the new wiping regime (20.7 to 9.4 per 100,000 patient bed days; p <0.005). Discussion Using a Poisson model we demonstrated that the average hospital acquisition rate of MRSA/100,000 patient bed days reduced by 6.3% per month after the introduction of the new universal wipe. Conclusion We suggest that using a simple one wipe system for nurse cleaning is an effective strategy to reduce the spread and incidence of healthcare associated MRSA.

【 授权许可】

Unknown